Common Side Effects
Common Side Effects
2025
2 Seasons
8.4
AnimationDramaComedySci-Fi & Fantasy

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

Episodes

Pilot
E1Feb 2, 202522m

Pilot

Marshall meets his old high school classmate Frances and lets her in on a world-changing secret.

Lakeshore Limited
E2Feb 2, 202523m

Lakeshore Limited

Marshall's forced on the run as the DEA pursues him.

Hildy
E3Feb 9, 202523m

Hildy

Marshall visits an old mentor as new pressures mount.

Dumpsite
E4Feb 16, 202523m

Dumpsite

Frances tracks down Marshall in an unlikely location.

Star-Tel-Lite
E5Feb 23, 202522m

Star-Tel-Lite

Marshall, Frances, and their crazy neighbors deal with the aftermath of a dangerous incident.

In the System
E6Mar 2, 202523m

In the System

Stuck in jail, Marshall faces new threats.

Blowfish
E7Mar 9, 202523m

Blowfish

A chance encounter offers a risky opportunity for escape.

Amelia & Wyatt
E8Mar 16, 202522m

Amelia & Wyatt

Marshall and his new ally make a bold move.

Cliff's Edge
E9Mar 23, 202523m

Cliff's Edge

Marshall's mushroom project grows out of hand.

Raid
E10Mar 30, 202523m

Raid

Dangerous forces converge on Marshall's camp.

Top Cast

Dave King

Dave King

Marshall Cuso (voice)

Emily Pendergast

Emily Pendergast

Frances Applewhite (voice)

Mike Judge

Mike Judge

Rick Kruger (voice)

Martha Kelly

Martha Kelly

Agent Harrington (voice)

Joseph Lee Anderson

Joseph Lee Anderson

Agent Copano (voice)